Functional Mechanisms of Yeast Cell Wall

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Action Mechanism of Yeast Cell Wall (Dual Active Core: β-Glucan + Mannan)

This content covers universal fundamental mechanisms and targeted mechanisms for monogastric animals, ruminants and aquatic species.

Main Active Ingredients of Yeast Cell Wall

The yeast cell wall consists of an inner layer of β-glucan and an outer layer of mannan (MOS), plus trace protein and chitin. These two core components work synergistically to deliver multiple benefits.

1. Universal Fundamental Mechanism

1. β-Glucan: Immune Activation, Anti-Stress & Antioxidation

1.Targeted immune activation

β-glucan binds to Dectin-1 receptors on animal immune cells, triggers the NF-κB signaling pathway, and stimulates the secretion of cytokines including IL-2, IL-6 and TNF-α. It elevates the phagocytic capacity of macrophages and the activity of NK cells, reinforces non-specific immunity, and boosts antibody titers after vaccination.

2.Stress alleviation

It lowers cortisol levels triggered by transportation, weaning, herd regrouping, cold and heat stress, so as to mitigate declined feed intake and production performance caused by stress.

3.Antioxidation and organ protection

β-glucan activates the Nrf2 antioxidant pathway, increases the activity of SOD and GSH-Px, and reduces MDA content. It relieves oxidative damage and protects the liver as well as intestinal barrier.

2. Mannan / Mannan Oligosaccharides (MOS): Pathogen Control, Gut/Rumen Regulation & Prebiotic Effect

1.Competitive adsorption against pathogens (physical inhibition, no drug resistance)

MOS matches the type I pili of enteric pathogens such as Escherichia coli, Salmonella and Clostridium perfringens. It competitively binds to these harmful bacteria, blocks their adhesion to intestinal walls, and eliminates them via excretion. This effectively reduces diarrhea and intestinal inflammation.

2.Premium prebiotic

MOS selectively nourishes beneficial microbes including lactic acid bacteria, bifidobacteria and ruminal cellulolytic bacteria, facilitating their proliferation and optimizing the overall microbial flora.

3.Mucosal barrier repair

It increases intestinal villus height, decreases crypt depth and thickens intestinal mucosa. This prevents endotoxin from entering the bloodstream and reduces systemic inflammatory response.

3. Extra Function: Mycotoxin Adsorption

Thanks to its porous network structure, yeast cell wall can physically adsorb mycotoxins like aflatoxin and zearalenone. It alleviates liver and kidney damage as well as production suppression induced by toxins.

2. Mechanisms for Different Livestock & Aquatic Species

Monogastric Animals (Poultry, Swine)

It mainly optimizes intestinal health and systemic immunity: reduces diarrhea incidence, improves survival rate and enhances feed conversion ratio. Since monogastric animals have no rumen degradation, conventional broken-cell yeast cell wall can work effectively.

Ruminants (Dairy Cattle, Beef Cattle, Calves — Key Differences)

1.Stabilize rumen microflora: MOS promotes the growth of propionate-producing bacteria and cellulolytic bacteria, improving the digestibility of crude fiber in silage and straw. It restrains excessive lactic acid accumulation, maintains stable rumen pH, and prevents ruminal acidosis and laminitis.

2.Raise dry matter intake (DMI), enabling more nutrients to be allocated for milk production and weight gain.

3.Special note: Conventional yeast cell wall is easily degraded by rumen microbes. Rumen-protected formulations are required to deliver active ingredients to the intestines for immune protection.

Aquatic Species

It enhances anti-stress ability and disease resistance of fish and shrimp, improves survival rate under aquatic environmental stress, and adsorbs waterborne toxins.

One-Sentence Core Summary

β-glucan exerts powerful immune regulation and anti-stress effects, while mannan suppresses pathogenic bacteria, feeds beneficial flora, protects mucosal tissues and stabilizes rumen environment. The two components work together to cut disease risks, boost feed intake and nutrient digestibility, and ultimately raise breeding productivity. This natural solution causes no drug residues or antibiotic resistance